Summary: Kinesthesia—the sense that tells us where our limbs are and how they are moving—is the essential feedback loop for natural, intuitive motor control. After a limb is amputated, that feedback loop is interrupted, and most prosthetic users must rely heavily on sight to guide movement. While mechanical vibration can activate residual muscle fibers and … Read more

Summary: The blood–brain barrier (BBB) is one of the body’s most effective protective interfaces, shielding the central nervous system from toxins and pathogens. That same protection, however, blocks more than 98% of small-molecule drugs and nearly all large-molecule therapeutics from reaching brain tissue. This barrier remains the primary obstacle to treating many neurological diseases, including … Read more

Summary: Stroke is a leading cause of long-term disability worldwide. Even after intensive early physiotherapy, many survivors continue to experience persistent upper-limb impairments, reduced hand dexterity, diminished touch sensation, and distorted body awareness. Conventional rehabilitation typically emphasizes movement training while sensory deficits and body representation problems remain largely untreated. This leaves a critical need for … Read more

Summary: In 1856, Göttingen anatomist Rudolf Wagner described a striking anatomical curiosity after examining a brain that was later misidentified as belonging to the mathematician Carl Friedrich Gauss: a tissue connection spanning the central fissure (central sulcus), the deep groove separating the frontal and parietal lobes. This rare “bridged” central sulcus resurfaced in anatomical literature … Read more

Summary: Attention-Deficit/Hyperactivity Disorder (ADHD) is a multifactorial neurodevelopmental condition shaped by both genetic predisposition and environmental influences. While heredity plays a major role in ADHD risk, identifying early modifiable factors that build neural resilience is a priority for pediatric research. A large longitudinal study from the University of Bergen reports a consistent association between exclusive … Read more

Summary: Decoding the first hours of human development has long been a central challenge in developmental biology. While decades of work in animal models—especially mice—have provided structural and conceptual guidance, investigating gene function directly in human embryos has been limited by the DNA damage caused by conventional genome-editing tools. Standard CRISPR/Cas9 approaches frequently introduce double-stranded … Read more

Summary: A pelvic schwannoma is an extremely rare, benign tumor that arises from the myelin sheath of peripheral nerves. When it grows deep in the retroperitoneal space of the lesser pelvis, it can mimic degenerative spinal disease by compressing sacral nerve roots, producing severe, persistent sciatic pain and risking lower limb paralysis. Because the pelvis … Read more

Summary: The phrase “being on the same wavelength” describes more than an emotional impression — it reflects a measurable neurobiological state. A decade of multidisciplinary research shows that during live, face-to-face interactions people’s neural rhythms align. By working with high schools, museums, and prominent performing artists, an international team of neuroscientists has mapped this social … Read more

Summary: Neurodegenerative disorders such as Alzheimer’s and Parkinson’s affect tens of millions worldwide and arise from complex, progressive cellular failures. One recurring observation in affected brains is the gradual accumulation of iron inside neurons. While small amounts of neuronal iron are benign for years, long-term buildup eventually undermines cellular defenses and contributes to slow, widespread … Read more

Summary: Subtle changes in walking speed and stride length are established early clinical signs of cognitive decline and dementia in humans. New research shows the same brain-body link exists in dogs. The study offers a more complete, objective view of canine cognitive dysfunction (CCD), commonly called dog dementia, and suggests gait monitoring could help veterinarians … Read more