Summary: Researchers using the artificial intelligence tool AI-MARRVEL together with functional fruit fly models have identified rare variants in the BRSK1 gene as the cause of a previously undiagnosed neurodevelopmental disorder. The study shows that reduced BRSK1 function disrupts microtubule organization and alters synaptic structure, producing developmental delays, speech and language deficits, autism traits, and … Read more

Summary: A retrospective clinical review found that adults with drug-resistant epilepsy who used recreational cannabis nearly every day experienced more than twice the annual rate of convulsive (tonic–clonic) seizures compared with nonusers. Frequent users also reached drug-resistant status and required specialized inpatient monitoring much faster—on average within five years of their first seizure versus 18 … Read more

Summary: Researchers at the University of Missouri report that bullfrog brains can manufacture ketone bodies locally when glucose becomes scarce, rather than relying solely on liver-produced ketones circulating in the blood. This on-site ketogenesis acts as an emergency metabolic reserve that sustains essential neural circuits during prolonged winter hibernation and low-oxygen conditions, and it points … Read more

Summary: A new study finds that accelerated biological aging in brain regions spared by a stroke plays a major role in language impairment and long-term recovery. Structural measures of brain “age” in uninjured tissue predicted the severity of aphasia and forecasted language recovery six months after patients received speech therapy combined with noninvasive brain stimulation. … Read more

Summary: An international umbrella review led by the European Academy of Neurology (EAN) in partnership with the Medical University of Vienna (MedUni Vienna) finds that chronic insomnia is linked to substantially higher risks for several serious health outcomes. The pooled evidence shows a 26% increased risk of stroke and a 28% rise in hospital admissions … Read more

Summary: Researchers at Washington University School of Medicine in St. Louis report that blocking immune cells from entering the brain preserves memory and brain tissue in a mouse model of Alzheimer’s-like tau pathology. Administering an antibody that inhibits CXCR3 reduced brain-infiltrating T cells by about half and protected roughly 40% more tissue in key memory … Read more

Summary: Neuroscientists report that human reaction speed systematically varies with the breathing cycle: responses to brief visual prompts were on average 41 milliseconds faster during exhalation than during inhalation, with an additional 21-millisecond benefit during the short pauses between breaths. This study provides the first continuous, phase-by-phase measurement linking respiration to millisecond-precision psychomotor performance, showing … Read more

Summary: Generative AI summaries can distort eyewitness memory, leading people to misremember events they personally observed. In a controlled experiment, exposure to misleading AI-generated summaries substantially reduced participants’ recall accuracy and implanted false details—even when readers were told the summaries were produced by AI. Key Facts: High Omission Rates: Across commercial multimodal models, including ChatGPT … Read more

Summary: Supported by a five-year K01 award of more than $943,000 from the National Institute on Drug Abuse (NIDA), neuroscientists at the University of Central Florida are investigating how nicotine reshapes neuronal mitochondria in the nucleus accumbens. By examining subcellular changes that promote drug-seeking behavior, the team aims to reveal molecular targets for better treatments … Read more

Summary: Researchers at the University of California, San Francisco (UCSF) have identified a set of 16 blood proteins whose levels change sharply during the menopausal transition. These molecular changes align with hormonal fluctuations—particularly in estradiol and follicle-stimulating hormone (FSH)—rather than with chronological age alone. In separate analyses of nearly 12,000 older women, higher midlife levels … Read more